Tadalafil weist eine hohe Selektivität gegenüber PDE5 auf und beeinflusst andere Isoenzyme nur geringfügig. Dadurch sind unerwünschte systemische Effekte auf Kreislauf oder Retina begrenzt. Die Proteinbindung im Plasma liegt bei über 90 %, was eine breite Gewebeverteilung ermöglicht. Die pharmakologische Wirkung zeigt sich unabhängig von der Nahrungsaufnahme und bleibt über viele Stunden konstant. Häufig beobachtete Nebenwirkungen stehen im Zusammenhang mit vasodilatatorischen Mechanismen, darunter Kopfschmerzen oder Flush-Symptome. Die Elimination erfolgt größtenteils fäkal, mit einem geringen Anteil über die Niere. Bei Vergleichen zwischen verschiedenen PDE5-Hemmern wird cialis kaufen aufgrund der langen Halbwertszeit oft als Referenz genannt.
We did it!!!
03.28.2011 
So, I used to be a "runner" (emphasis on the quotation marks.) Throughout all of the training and long runs over the last several months I never really felt like a true runner. I was just trying, just one of those people who hoped to be a real runner someday. Well, guess what, now I AM a runner. No quotation marks.
Yesterday, I finished my first half marathon-along with my hubs (whose 1st time it was as well) and my parents (both seasoned marathon veterans.) It was one of the most rewarding moments of my life. To see everyone there together, all for a beautiful cause, everyone cheering each other on, smiling and laughing-it was a day I will never forget. Breast cancer is a horrible disease, and no one deserves to go through it. I have so much respect and love for all of the survivors (one in particular-KJ!) and those who have battled bravely. The thing that got me through the race was thinking of these amazing women. Thank you everyone for your support and love throughout this journey. I couldn't have done it without you!
So, here's what I learned through the training and half marathon experience:
1. If you really commit, and pray, you can do ANYTHING.
2. It is 50% physical and 50% mental.
3. I am stronger than I think I am.
4. Anyone can be an athlete.
5. My husband and parents are the most amazing people in the world (well, I already knew that.)
Yes, I am still tired. And really sore. But I can't wait for my next run.
XO
-L
30 before 30, Run Lauren Run! in Health, Life
Reader Comments (6)
wow...congrats to all of you.
So proud of you guys! It was awesome to see you ~ miss ya!
CONGRATS Lauren!!!! What an amazing feat!! I'm half way through my training and seeing your photos has inspired me to keep going. Whoo-hoo!!
Congratulations, Lauren! What an awesome accomplishment. You should be really proud. :)
you are too cool, definitely making me want to try it! and you don't even have a wedding dress you are trying to fit in to!
Oh my gosh! That is so amazing. Great job girl! That is an impressive accomplishment.